London.  December 1888.  221B Baker Street.  The notorious and as-yet undiscovered genius, Vincent van Gogh presents the master-sleuth Sherlock Holmes with a most unusual case.  Aided by his partner Dr. Watson and his paramour Irene Adler, the trio embark on a rousing adventure.  Aided by Oscar Wilde, the world's greatest detective dashes forth to solve one of the most audacious crimes of the Victorian era and uncover a Post-Impressionist conspiracy.